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Issue:- 12 July  2012

NEW TREATMENT HAILED AS 'A POTENTIAL BREAKTHROUGH IN THE BATTLE AGAINST
HEART DISEASE AND STROKES
'

SYNEXUS, the world's largest multinational company dedicated to the successful recruitment and running of clinical studies with a Dedicated Clinical Research Centre in Merseyside, is currently recruiting patients for a study which is assessing a new treatment which may help reduce the incidence of further heart attacks or strokes in people who suffer with cardiovascular disease (CVD).

The new medication, which has received high profile coverage in the national media including the Daily Mail and Daily Express, is a 'cholesterol busting' injection which has already been tested in the US and produced promising results. Doctors have hailed it as 'a potential breakthrough in the battle against heart disease and strokes'. High cholesterol levels in the blood, especially high LDL-C levels (known as bad cholesterol) is one of the main risk factors for CVD and strokes. Current treatments for lowering cholesterol levels include taking 'statins' and although statin treatment is effective in lowering LDL-C, it does not reduce it to desirable levels in all cases.

Cardiovascular disease (CVD) is a general term for a disease of the heart or blood vessels. Blood flow to the heart, brain or body is reduced because of a blood clot or a build-up of fatty deposits inside an artery, leading to hardening and narrowing of the artery. The three main types of CVD are coronary heart disease, stroke and peripheral arterial disease. Cardiovascular Disease is responsible for nearly half of all deaths in Europe each year with 191,000 deaths in the UK alone. Currently there are nearly 2.7 million people in the UK living with CVD[2].

The study that Synexus is currently running to assess this new medication may be suitable for those who:-

Are over 30 years old

Have been identified as already having cardiovascular disease

Those at risk of developing cardiovascular disease

Are currently being treated with cholesterol lowering medications such as Simvastatin (Zocor), Atorvastatin (Lipitor) or Rosuvastatin (Crestor)

The study will involve patients taking medication on top of their usual cholesterol lowering medication.  Synexus is currently recruiting patients for this study at its Dedicated Clinical Research Centres in Merseyside.  Those who would like to find out more or are interested in participating in this study should contact their nearest centre and quote the relevant reference number Merseyside:- 0151 550 9951. Ref:- 8090

There is no obligation for people to participate and if they do decide to take part, their GP will be kept fully informed of their involvement. Patients who are accepted onto the study will receive financial compensation and will be reimbursed for all reasonable out of pocket expenses if they are accepted onto the study.

Synexus has many years experience in conducting a wide range of clinical studies. The purpose of a clinical research study is to answer important questions about a new treatment, for example; does it improve a person's health and which dose of the medicine works best?

Each year, thousands of patients take part in clinical studies at Synexus' Dedicated Clinical Research Centres. There are many different studies running at each of the Centres including treatments for conditions such as osteoporosis, smoking cessation, insomnia, asthma and childhood eczema.  Participating in a Synexus clinical study means patients receive increased medical attention and may benefit from medications that aren't yet available to other sufferers of their condition, while making a positive contribution to the health of future generations.  For more information about Synexus and the other studies that it is currently conducting visit:- improvinghealth.com.

White Paper Weak on Metering

"LACKING ambition and urgency", the Chartered Institution of Water and Environmental Management (CIWEM) welcomes the conclusions of the Environment, Food and Rural Affairs Committee report on the Water White Paper.

CIWEM is pleased to see the Committee agreeing with CIWEM's position that the Government has been weak on water metering. The Water White Paper, published in December 2011, lacks any target to increase levels of metering; but the Committee has recommended that the Government take on board the level of ambition suggested in the Walker Review; of achieving 80% metering coverage by 2020.

CIWEM was particularly alarmed by the White Paper's proclamation:- "water is relatively cheap compared to many other household bills, and we want it to stay that way". The document contains a clear contradiction: how can we value water and not take it for granted, but yet not pay a price for water that properly recognises its true value? CIWEM believes the fairest way to ensure this is to establish widespread metering allied to flexible and social tariffs.

Paying for what we use is not only the fairest way to pay for water, it is also the only way to build the clear picture of patterns of water consumption which will be needed to move forward sustainably and to ensure that water is affordable for all in the long term.

Politically, metering may be seen as difficult but recent research* has shown that the public are prepared to support water metering measures, but only if the Government takes the lead and if the measures that are introduced are seen to affect everyone equally, or in a way that rewards those who avoid wasting water and penalises those whose use is excessive.

CIWEM is also pleased to see the Committee calling for more urgency in the reform of the abstraction regime and the encouragement of sustainable drainage systems (SUDS). We look forward to seeing the Government addressing the Committee's recommendations in their draft Water Bill.

CIWEM Executive Director, Nick Reeves OBE, says:- "The Water White Paper misses an opportunity to promote the retention of affordable water for all who use water wisely and to charge those who use high quantities higher prices than they now face. It is naïve to assume that people who use excessive amounts of water will change their behaviour to the degree needed through anything but higher prices."

*Research by the Fabian Society, December 2011, Water Use in Southern England.

WANTED - ANTHONY DUFFY

MERSEYSIDE Police are appealing for information to trace the whereabouts of a man from north Liverpool who is wanted for recall to prison. Antony Duffy, aged 34, of no fixed abode, was released on license on 28 March 2012, from HMP Buckley where he was serving a 2 year sentence for a stabbing in January 2011. Duffy has failed to comply with the conditions of his license by not residing at the approved address and is now wanted for recall to prison. Officers are searching for Duffy and urge anyone with any information regarding his whereabouts to call Merseyside Police on:- 101, or Crimestoppers, anonymously, on:- 0800 555 111.

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