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Weekly Edition - Published  8 February 2015


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Wirral NHS Trust leads the way in global fight against Alzheimer's

Photo 1 – staff from CWP’s research team

STAFF and patients at Wirral mental health Trust CWP are taking part in a pioneering research programme that could lead to a new way combat Alzheimer's.

Members of Cheshire and Wirral Partnership NHS Foundation Trust's (CWP) research team, led by Consultant Psychiatrist Joe Ferran, along with 6 local service users, are working with Swiss pharmaceutical and research company AC Immune to trial a brand new vaccine that inhibits the growth of the neurofibrillary tangles in the brain (a typical characteristic of the disease) and aims to slow the cognitive decline in Alzheimer's disease.

CWP is working closely with colleagues in the Clinical Research Unit at Royal Liverpool Hospital to provide the trial therapy to 6 Wirral-based patients. This is a significant number of the programme's overall patient cohort, which includes just ten in the UK and 24 globally. If successful, the vaccine, called ACI-35, could pave the way for a simple jab that slows the effects of the disease.

Dr Anushta Sivananthan, Consultant Psychiatrist and Medical Director at CWP, said:- "I am delighted that CWP is able to be at the forefront of such international research. There are currently over 850,000 people in the UK living with dementia, and Alzheimer's makes up 62% of these cases. Research into this field is absolutely vital, and as an NHS Trust we are committed to working in partnership to do all we can to support research and innovation in this area as well as provide care to existing sufferers."

Pat Mottram, CWP Research and Effectiveness Manager, said:- "We had to screen over 1500 people to ensure we found suitable people for this study. We have just finished recruiting for this phase of the trial. If the results look promising then we will be recruiting further patients in late summer."


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